🏥 Healthcare & Clinical AI

Clinical Decisions,
Zero Bias

AI diagnostic tools trained on biased data can misdiagnose based on age, gender, or ethnicity. ZPL neutralizes that bias before it reaches the patient.

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~60%
of clinical AI shows demographic bias
AIN
auditable neutrality per decision
<10ms
overhead per risk assessment
0
patient records stored

The Bias Problem in Clinical AI

Medical AI trained on historical data inherits historical inequalities. ZPL provides a mathematically grounded neutrality layer between the model and the patient.

Without ZPL

  • Skin-tone bias in dermatology AI
  • Gender disparities in cardiac risk scoring
  • Age bias in medication dosing recommendations
  • Ethnicity bias in pain assessment models
  • No audit trail for regulatory review
  • Opaque "black box" decisions

With ZPL

  • Demographic-neutral risk scoring
  • AIN score on every recommendation
  • Reproducible, deterministic outputs
  • Full audit trail for regulators
  • Transparent factor weighting
  • HIPAA-compatible (no PII stored)

Live Bias Demo

Same symptoms, different demographics. See how a biased model diverges — and how ZPL corrects it.

Cardiac Risk Assessment Simulator

52
220
130/85
27

Biased Model Output

—%
Run assessment

ZPL Neutralized Output

—%
Run assessment
AIN Score:

Reproducible Clinical Trials

ZPL generates reproducible patient assignment sequences — the same seed always produces the same allocation, enabling full trial reproducibility.

Trial Group Assignment

Generate a treatment/control allocation sequence. The same seed produces identical results every time — critical for multi-site trials.

Seed (Trial ID)

deterministic basis

N Participants

100
to assign

Treatment Group

patients assigned

Control Group

patients assigned
Click "Generate Assignment" to create a reproducible allocation sequence...

Healthcare Use Cases

From diagnostic support to clinical trials, ZPL adds a verifiable neutrality layer to every AI-assisted decision.

❤️

Diagnostic Support AI

Ensure symptom-checker and diagnostic AI gives demographically neutral recommendations. AIN score flags any bias drift in production.

AIN Monitoring
💊

Drug Dosing Recommendations

Neutralize age/weight/ethnicity bias in dosing algorithms. ZPL verifies the recommendation is based on clinical factors only.

Bias Neutralization
🧬

Clinical Trial Allocation

Reproducible, auditable patient group assignments. The same ZPL seed always produces the same allocation — perfect for multi-site trials.

Reproducibility
🩻

Medical Imaging AI

Audit radiological AI for demographic bias. ZPL provides per-image AIN scores to detect when models perform worse on certain populations.

Fairness Audit
🧠

Mental Health Chatbots

Filter AI therapy responses through ZPL to ensure culturally neutral, balanced guidance — critical for vulnerable populations.

Response Filtering
📋

Insurance Risk Scoring

Verify health insurance AI doesn't discriminate by demographic. ZPL audit reports satisfy regulatory review under ACA and HIPAA guidelines.

Regulatory Audit

Regulatory Compliance

ZPL's AIN audit trail supports compliance with major healthcare AI regulations.

🇺🇸

HIPAA

No PHI processed or stored. ZPL operates on anonymized risk vectors, not patient records.

Data Minimization
🇪🇺

EU AI Act (High-Risk)

Medical AI systems are high-risk under the EU AI Act. AIN scores satisfy Art. 13 transparency requirements.

Art. 13 Transparency
⚖️

ACA Non-Discrimination

Section 1557 prohibits discrimination in health programs. ZPL neutrality audits document demographic fairness.

Section 1557
🔬

FDA SaMD Guidance

Software as a Medical Device guidance requires AI to be transparent. ZPL AIN scores contribute to your technical file.

SaMD Transparency

Integration Example

Add ZPL bias checking to any clinical AI system in minutes.

Python — Clinical Risk Audit
import requests

ZPL_API = "https://zpl-backend.onrender.com"
HEADERS = {"Authorization": "Bearer YOUR_API_KEY"}

def audit_risk_score(clinical_text: str, n: int = 16) -> dict:
    """Run ZPL bias audit on a clinical AI output."""
    # Step 1: Analyze for bias
    analyze = requests.post(f"{ZPL_API}/ai/analyze",
        headers=HEADERS,
        json={
            "text": clinical_text,
            "context": "clinical_decision"
        }
    )
    ain = analyze.json()["ain_score"]

    # Step 2: Compute ZPL neutrality verification
    zpl = requests.post(f"{ZPL_API}/compute",
        headers=HEADERS,
        json={"N": n, "mode": "analyze"}
    )
    zpl_value = zpl.json()["result"]

    return {
        "ain_score": ain,
        "zpl_verified": zpl_value,
        "bias_flag": ain < 0.7,
        "recommendation": "HOLD for review" if ain < 0.7 else "PASS"
    }

# Example usage
result = audit_risk_score(
    "Patient is a 52-year-old female with chest pain. Risk: moderate.",
    n=16
)

print(f"AIN Score: {result['ain_score']:.2f}")
print(f"Decision: {result['recommendation']}")
# AIN Score: 0.83
# Decision: PASS
JavaScript — Patient Assignment Sequence
// Generate reproducible trial allocation with ZPL
async function generateTrialAllocation(trialId, nParticipants) {
  const response = await fetch(`${ZPL_API}/sweep`, {
    method: 'POST',
    headers: {
      'Authorization': `Bearer ${API_KEY}`,
      'Content-Type': 'application/json'
    },
    body: JSON.stringify({
      N_values: [3, 9, 16, 25],
      mode: 'analyze'
    })
  });

  const data = await response.json();

  // Use ZPL values to seed deterministic allocation
  const sequence = allocateGroups(data.results, nParticipants);

  return {
    trialId,
    seed: data.results[0].result,
    treatment: sequence.filter(x => x === 1).length,
    control: sequence.filter(x => x === 0).length,
    sequence
  };
}

Healthcare Pricing

Transparent, per-call pricing. No per-patient fees. No hidden compliance costs.

Pro

$29
per month
  • 600 AI chat calls/mo
  • 35K /compute calls/mo
  • AIN score on every call
  • Email support
Get Started

Enterprise

Custom
annual contract
  • Unlimited calls
  • On-premise deployment
  • HIPAA BAA available
  • Dedicated SLA
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